The Effect of Seasonality on Pregnancy Rate in Patients Undergoing Intracytoplasmic Sperm Injection

ckground: Assisted Reproduction Technology (ART) is affected by variable factors including cause of infertility, type of treatment, ovulation induction methods and environmental factors. There is no consensus on the effects of temperature and seasonal changes and ART outcome.The aim of present study was to evaluate the effect of seasonality on ICSI outcome. Methods: Three thousand six hundred seventy patients undergoing their first ICSI cycle during 2011 to 2015 were retrospectively evaluated in thepresent study .Data were compared between the four seasons. The implantation and pregnancy rate was considered as primary outcome.Results: There was no significant difference in the sperm morphology, grade A quality embryos, fertilization rate and number of transferred embryos. Total number of retrieved oocytes were significantly higher in summer and winter (P=0.004). There was significant differences in sperm motility (spring: 64.3±18.1, summer: 61.4±18.2, autumn: 62±18.3, winter: 65.3±18.3,P=0.0001) and metaphase II oocytes in different seasons (spring: 7.8±5.6, summer: 8.8±6.3, autumn: 8±5.7, winter: 8.2±5.8, P=0.015). Total number of sperm was significantly higher in spring and winter (P=0.0001). The highest implantation (P=0.0001) and pregnancy rate (P=0.001) were seen in summer. Conclusion: According to the results, it can beconcluded the effect of seasonal variation on the rate of pregnancy and implantation on infertile couples. It seems that together with other factors seasonal changes should therefore be considered in managing of patients

کلیدواژه ها:

Intracytoplasmic Sperm Injections ، Seasonal Variation ، Infertility