An Overview Of Generations And New Methods Of Dna Sequencing In Genetic Diseases And Cancer

DNA sequencing is currently a powerful technique for decoding genetic information encoded in DNA with high resolution and industrial scalability. This technology has opened new frontiers in genomic research, clinical diagnostics, and personalized medicine, driving advancements in various fields such as cancer research, hereditary diseases, and evolutionary biology. With the advent of Next Generation Sequencing (NGS), gene sequencing and the diagnosis of genetic diseases have entered a new realm. This technique allows for genetic diagnosis of many diseases and syndromes, including congenital disorders previously categorized as 'of unknown causes' due to technical limitations. The NGS technique comprises a series of methods including initial preparation and fragmentation of the genome sample, sequencing, imaging and visualization, assembly of sequenced fragments, and data analysis. Decoding the human genome provides critical clues about the genetics of diseases and facilitates the development of more specialized preventive measures. Diagnostic and therapeutic strategies over the past decade have extensively focused on the use of sequencing and genomic mapping.

کلیدواژه ها:

DNA sequencing ، decoding genetic information ، cancer ، hereditary diseases ، diagnostics ، therapeutics