The death rate of COVID-۱۹ infection in different SARS-CoV-۲ variants was related to C-reactive protein gene polymorphisms

The serum level of C-reactive protein (CRP) is a significant independent risk factor for Coronavirus disease ۲۰۱۹ (COVID-۱۹). A link was found between serum CRP and genetic diversity within the CRP gene in earlier research. This study examined whether CRP rs۱۲۰۵ and rs۱۸۰۰۹۴۷ polymorphisms were associated with COVID-۱۹ mortality among various severe acute respiratory syndrome Coronavirus ۲ (SARS-CoV-۲) variants.Methods: We genotyped CRP rs۱۲۰۵ and rs۱۸۰۰۹۴۷ polymorphisms in ۲,۰۲۳ deceased and ۲,۳۰۷ recovered patients using the polymerase chain reaction-restriction fragment length polymorphism method.