Spinal Burkitt lymphoma as an uncommon first manifestation of AIDS: A case report

Background: Patients struggling with AIDS are significantly at higher risk of developing lymphoma. Lymphoma usually occurs in uncommon extra-nodal sites in immune deficient patients. In current study, we have aimed to introduce a case with spinal Burkitt lymphoma (BL) as the first manifestation of HIV.Presentation of case: A ۳۶-year-old drug addicted, the married male was free of drug abuse since ۱۰ years ago, referred to Al-Zahra Hospital with a complaint of back pain that radiated to lower limb. Lower limb force was ۴.۵. He did not have any sensory deficiency. Intervertebral disk protrusion at the L۵-S۱ level and paravertebral abscess at T۱۰-T۱۱ levels were found in MRI. The symptoms were not relieved by usual painkillers. The patient was ill at admission and he had nausea and also oral candidiasis. Due to the history of IV-drug using, HIV tests were sent for him and viral load was ۵۲۱۰۷ copies/ml and genotype indicated infection of HIV-۱. Number of CD۴ cells was checked as well. The number equaled ۲۴. After necessary consultants, he underwent decompressive laminectomy and fixation and sample biopsy in order of infection/neoplasm ruling-out was sent. Results of biopsy showed histological and immunohistochemical findings in favor of Burkitt lymphoma. Conclusion: BL can be the first manifestation of HIV, as a result, uncommon site of BL can act as a clue to the early diagnosis of HIV/AIDS.

کلیدواژه ها:

Acquired Immunodeficiency Syndrome ، Burkitt lymphoma ، HIV