The Constituent Elements of The Synthesis of Nanoparticles in Biological Nano Robots (Nano Bio Robots), One of The Latest Methods in the Field of Nanoelectronics Technology

Note: DNA Origami is  one of the newest techniques of using DNA as the building blocks for the synthesis of nanoparticles in biological nano robots (Nano bio Robots)  . This is one of the latest methods in the field of nanoelectronics technology, which has its own limitations and opportunities. "Origami" is a Japanese word that means folding a simple sheet into a desired shape with a specific dimension.

Although DNA is the natural choice for making the active structures of DNA origami nano robots  . It is not for nanorobotics applications, but due to the lack of structural and catalytic diversity, molecular walkers on origami and switches are also possible.  DNA  origami nanorobots  display computational capacities and a pre-programmed task inside a living organism. In the structure of  the DNA nanorobot they created, there is an open DNA tube that consists of a The side has a hinge and can be closed.  The drug-loaded DNA tube  is bound by a DNA aptamer and  configured to identify and search for disease-related proteins.  When DNA origami nanorobots   hit infected cells, the aptamers dissociate and release the drug.

DNA origami  takes a completely different approach from a multi-strand design.  Usually, single-stranded circular genomic DNA of nanobots (Nano bio Robot) is used as a scaffold, and hundreds of short auxiliary strands called staples are used to assemble the longer scaffold into a specific structure. In the folding process, the scaffold DNA It acts as a guide or a seed, which increases the folding efficiency and resistance to the stoichiometry of the filaments in the Nano bio Robot.

Conclusion :

In general, DNA Origami is  one of the newest techniques of using DNA as the constituent elements of the synthesis of nanoparticles in biological nano robots (Nano bio Robots)  . This is one of the latest methods in the field of nanoelectronics technology, which has its own limitations and opportunities. "Origami" is a Japanese word that means folding a simple sheet into a desired shape with a specific dimension.