HN-01740124_Effect of probiotics and synbiotics on selected anthropometric and biochemical measures in women with polycystic ovary syndrome: A systematic review and meta-analysis
محل انتشار: سومین همایش بین المللی تغذیه بالینی ایران
سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 343
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شناسه ملی سند علمی:
ICNC03_109
تاریخ نمایه سازی: 12 اسفند 1398
چکیده مقاله:
Introduction: This study aimed to systematically review randomized clinical trials (RCTs) to clarify the effects of pro-/synbiotic supplementation on anthropometric and biochemical measurements in women with polycystic ovary syndrome (PCOS).Methods: PubMed, Scopus, ISI Web of Science, Cochrane Library, and Google Scholar were searched through September 2018. Eight RCTs (nine treatment arms) were included.Results: Pro-/synbiotic supplementation significantly reduced fasting blood sugar (−2.52 mg/dl, 95% confidence interval (CI): −4.10 to −0.95), insulin (−2.27 μIU/mL, 95% CI: −3.40 to −1.14), homeostasis model assessment for insulin resistance index (−0.69, 95% CI: −0.98 to −0.40), C-reactive protein (−1.69 Hedges’, 95% CI: −3.00 to −0.38), and total testosterone (−0.12 ng/mL, 95% CI: −0.17 to −0.08) in women with PCOS.Conclusion: However, changes in the mean difference of weight and body mass index did not reach a statistically significant level. The findings suggest that pro-/synbiotic supplementation may improve glucose homeostasis parameters, hormonal, and inflammatory indices in women with PCOS.
کلیدواژه ها:
نویسندگان
Shima Sharifi
Student Research Committee, Department of Clinical Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
Abed Ghavami
Student Research Committee, Department of Clinical Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran