The current applied researches in Bio-Analysis Lab

The current applied researches in Bio-Analysis Lab are based on specificity of the bioreceptorstoward their targets which are categorized to biosensors, biofuel cells, nanozymesand nanomedicine. Bio-receptors could be divided to enzymes, antibodies, nucleic acids,tissues or even single cells. Here some example of applied researches are presented: i) Thenanocomposites consisting of functionalized single/multi-wall carbon nanotubes either aloneor incorporating with the metallic nano-particles such as gold and silver, or room temperatureionic liquids could be used for electrochemical biosensor development since they increase theelectrical conductivity, electron transfer rate and the reversibility of the redox proteins. ii)Different types of optical biosensors especially for cancer diagnosis at early stages wasdeveloped by incorporating different types of metallic nanoparticles including gold,branched gold and porous gold nanoparticles and DNA or micro RNA probes. iii) Bysynthesizing different type of chemical complexes such as copper-cysteine and coveringthose by proteins such as albumine or appoferritine, superoxide dismutase (SOD) mimeticnanozymes were developed. iv) Some metallic nanoparticles such as silver, cadmium andcopper when coated with bovine serum albumin could act as chemotherapeutic agent againstinvasive human breast cancer. v) To develop enzyme/microbial biofuel cell, differentbioanodes was designed. Either a redox enzymes was immobilized or an electrogenicbacterium could be grown on the woven carbon fiber filament coated with a nanocompositeconsisting of NH2-MWCNTs and RTIL. As Conclusion, during last two decades differenttypes of nanomaterials were developed in our lab to facilitate the signal transduction of bioreceptors.

کلیدواژه ها:

Bio-Analysis Lab ، Nanozymes ، Nanotechnology ، Biosensors ، Nanoparticles ، Biofuel cell