The effect of elevated levels of serum anti mullerian hormone on the quality of the embryo in infertile women undergoing assisted reproductive technology

Background: Anti-Mullerian Hormone (AMH) is produced by the granulosa cells of preantral and antral small follicles. AMH is the most significant predictor of embryo quality and a known biomarker of ovarian function. AMH level can be considered as an important factor to evaluate women s infertility at reproductive age. The purpose of this study was to investigate the correlation between increased AMH concentration and the quality of embryo in infertile women at reproductive age.Methods: In this study, the AMH levels were analyzed in 85 34-to-39-year-old women where 45 of them were within a normal AMH level and 40 of them had an elevated level. Data collected from this study was analyzed through the independent sample T test method. The mean was significantly different from the P value with an accuracy of less than 0.05.Result: The comparison between women with normal and elevated AMH indicates that those with elevated AMH have a significant increase on percentage of C grade embryo and it doesn t show significant differences in the other parameters of embryo quality.Conclusion: The previous studies have indicated that levels of serum AMH are effective on the quality of embryos. Therefore, abnormal levels of AMH might be effective on the quality of embryo. This study suggests that the level of AMH hormone in women can be an effective tool for assessment oocyte and embryo quality.

کلیدواژه ها:

Assisted reproductive technology ، Biomarker ، Infertility ، Pregnancy ، Quality of embryo ، Anti mullerian hormone