The first study of bovine immunodeficiency virus (BIV) and brucellosis co-infection in west-central Iran

BACKGROUND: BIV is a well-known bovine immunosuppressivecause, but its pathogenesis has not been well characterized.In recent years, it has been hypothesized that infection with BIVmight predispose cattle to be infected by other agents. OBJECTIVE:This study was performed to investigate of BIV and Brucellaco-infection so that in the future more studies will be doneon the issue of predisposing cattle to other microorganisms likeBrucella after BIV infection. METHODS: Blood samples werecollected from a total of 2290 cattle in Iran (490 and 1800 cattlein non-industrial and industrial dairy farms, respectivelyfrom Isfahan and Chaharmahal and Bakhtiari provinces). TheBIV-positive animals were detected by Lab-ELISA and nestedPCR tests. RESULTS: In this study, the overall prevalence ofBIV in Iran was 1.61% (4.5% and 0.83% in non-industrial andindustrial dairy farms, respectively). CONCLUSIONS: There wasa statistically significant relationship between BIV status andBrucella infection using Chi square and Pearson’s correlationcoefficient test for all of the samples (p=0.0001, r=0.24), samplesfrom Chaharmahal and Bakhtiari (p=0.044, r=0.13) andfrom industrial farms in Isfahan (p=0.001, r=0.074).

کلیدواژه ها:

Bovine immunodeficiency virus ، Brucella ، seroprevalence