Low-level laser therapy synergistically improves the effects of natural killer cell mediatedimmunotherapy in cancer

سال انتشار: 1402
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 272

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شناسه ملی سند علمی:

BIOC03_163

تاریخ نمایه سازی: 6 خرداد 1403

چکیده مقاله:

Different kinds of treatments have been developed to fight cancers. The types of treatment sthat patients receive will be dependent on the cancer type and how advanced it is. Somepatients are treated with only one way, but most patients receive combination therapies, suchas surgery followed by chemotherapy, immunotherapy and/or radiation therapy. low-levellaser therapy (LLLT), also known as photobiomodulation (PBM) therapy, is a low-powermonochromatic and coherent light that has been used successfully for healing injuries andcombat malignancies. Immune cell therapy is a promising approach that is applied to fightcancers using cellular immune system. In this regard, natural killer (NK) cells belonging toinnate immunity are widely used to kill cancer cells. In this article, we hypothesize to explainhow PBM therapy can enforce the effect of NK cell-mediated immunotherapy on cancers.

نویسندگان

Najmeh Malekzadeh Gonabadi

Department of Biology, University of Sistan and Baluchestan, Zahedan, Iran.

Sahar Shojaei

Middle East Gene and Cell Therapy Company, Tehran, Iran.

Seyed Mehdi Alavi

Department of Plant Biotechnology, National Institute for Genetic Engineering andBiotechnology. Tehran, Iran

Dor Mohammad KordiTamandani

Department of Biology, University of Sistan and Baluchestan, Zahedan, Iran.

Mehdi Shamsara

Department of Animal Biotechnology, National Institute for Genetic Engineering andBiotechnology, Tehran, Iran.