HN-01400083_Ketogenic Diet and Obesity: A Systematic Review

Introduction: Obesity is a main risk factor for a number of cardiovascular and metabolic disorders such as dyslipidemia, diabetes, hypertension and also certain types of cancers (1). Different methods for reducing weight using diminished calorie and fat intake combined with exersice have lost to demonstrate sustained long-term effects (2-4). One of the most studied strategies in the recent years for weight reduction is the ketogenic diet, diet high in fat and low in carbohydrate (5). This systematic review will evaluate the recent scientific literature on the efficacy of the ketogenic diet promoting weight loss.Methods: Pubmed, Scopus and Google scholar databases were searched using relevant keywords.Results: The evidence reviewed in this article illustrated that a period of low carbohydrate ketogenic diet may help to control hunger and may promote fat oxidative metabolism and thus decrease body weight. In addition new kinds of ketogenic diets using meals that imitate carbohydrate rich foods could better the admission of the diet (6). Attention should be paied to renal function of patients and the transition phase from ketogenic diet to a normal diet that should be step-by-step and well controlled (7). The course of ketogenic diet may range from 2-3 weeks to 6-12 months that the first period induce the physiological ketosis and the later follow a general precautionary principle (8).Conclusion: In summary ketogenic diet can be a helpful tool to target obesity and is safe to use for a longer period of time than previously exhibited.

کلیدواژه ها:

ketogenic diet ، obesity ، metabolism ، systematic review