Diagnosis of MS Plaques Using MRI Protocols(STIR) Before and After Repair of Myelin Sheath by Image Processing

Multiple sclerosis is a chronic inflammatory demyelinating disease of the central nervous system (CNS), which gives rise to focallesions in the gray and white matter and to diffuse in the entire brain. Inflammation is dominated by major histocompatibility complex Class I restricted T-cells. Activated microglia are seen in close contact with degenerating myelin sheaths, axons, and neurons. The purpose of this study was to design and introduce a diagnosis of MS plaques using MRI protocols (STIR) before and after repair of myelin sheath by image processing. Materials and Methods: This research was a software designing of many MRI images were analyzed with the software designer. The designed software was in MATLAB. In this study; we used image processing techniques such as; noise removing, edge denotation, separate of area with high density and contrast increasing for analysis The results of all lesion diagnostics were analyzed and compared inthe pathologist’s report. Results: Designed software enables the present MRI images analyzes them pixel by pixel. This software in addition evaluates the areas of lesions and shown them without viewer diagnosis completely. Final results of diagnostic software analysis showed high sensitivity. Conclusion: Contemporary assessments of morphologic and physiologic traits of lesions by a computer aided diagnostic software can improve the radiologist’s and neurologist precision and decrease reading time of bulk images of MRI. Using this software to increase the accuracy of the lesions detection is suggested.