Effect of 8 weeks regular endurance training on galectin-3 changes after a strenuous aerobic exercise

سال انتشار: 1396
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 371

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شناسه ملی سند علمی:

JR_JPAH-1-3_003

تاریخ نمایه سازی: 4 تیر 1398

چکیده مقاله:

Introduction: Galectin-3 (gal-3) is a member of the lectin family that is associate with heart failure, including myofibroblast proliferation, fibrogenesis, tissue repair, inflammation, and ventricular remodeling. Although gal-3 increases after high intensity exercise, regular training may attenuate these conditions. The aim of present study was to investigate the effect of 8 weeks regular endurance training on galectin-3 changes after a strenuous aerobic exercise. Material & Methods: Elevenhealthy young men (aged: 20.8 ± 1.8 years; ± SD) volunteered to participate in this study. All the subjects were performed Repeated High-Intensity Endurance Test (RHIET) as a strenuous aerobic exercise. Thereafter, the subjects were performed endurance training 3 days a week for 8 weeks at an intensity corresponding to 60-75% individual heart rate reserve (HRR) for 30-45 min. After the 8 weeks intervention, the RHIET was performed a gain. Blood samples were taken at baseline (1st step), immediately after the RHIET (2nd step), 48h after 8 weeks intervention (3rd step) and immediately after the second RHIET (4th step). Results: The results showed that gal-3 level was increased after the first strenuous aerobic exercise (P<0.05). After 8 weeks exercise training, gal-3 was decreased compared to 2nd step of blood sampling (P<0.05) and no significant change was observed in gal-3 in this step compare to the baseline. The results indicated that gal-3 level was lower after the second strenuous aerobic exercise than compare to the after the first strenuous aerobic exercise (P<0.05). Conclusions: The results suggest regular endurance training with specific intensity and duration utilized in this study, attenuate gal-3 changes after single session of strenuous aerobic exercise.

نویسندگان

Nooshin Khajeian

Department of Exercise physiology, Marvdasht branch, Islamic Azad University, Marvdasht, Iran

Mehrzad Moghadasi

Department of Exercise physiology, Shiraz branch, Islamic Azad University, Shiraz, Iran

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