Application of artificial neural network as an artificial intelligence method in chemistry
سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 612
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شناسه ملی سند علمی:
EMCE04_259
تاریخ نمایه سازی: 21 خرداد 1398
چکیده مقاله:
In this research, artificial neural network (ANN) as an intelligent method combined with spectrophotometry technique, were used for determination of Sofosbuvir (SOF) and Ledipasvir (LED) in synthetic mixtures and Harvoni tablet simultaneously. Feed-forward back-propagation network with different training algorithms was applied in artificial neural network method. Finally, this method was compared to the high- performance liquid chromatography (HPLC) as a reference method. Furthermore, the obtained results of the one-way analysis of variance (ANOVA) test at the 95 % confidence level showed that there was no significant difference between the proposed and reference method.
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نویسندگان
Negin Safakhoo
Department of Chemistry, North Tehran Branch, Islamic Azad University, Tehran, Iran
Mahmoud Reza Sohrabi
Department of Chemistry, North Tehran Branch, Islamic Azad University, Tehran, Iran
Shirin Mofavvaz
Department of Chemistry, Shahreza Branch, Islamic Azad University, Shahreza, Isfahan, Iran