Design of an electrochemical bisphenol A sensor based upon magnetic nanoparticles modified with Au

Production and consumption of plastics have been grown globally from 1950. Bisphenol A (BPA) can be migrate from its containers (polycarbonate plastic and epoxy resins) into a variety of foods and drinks [1]. Estrogenicity of BPA in vitro is similar to the 17β-estradiol which can mimic hormons and disrupt endocrine function. Therefore, BPA display an adverse effect in humanimmune function [2]. Therefore, it is quite logical that detection of BPA with the various used analytical methods. Among them, electrochemical techniques are the one of acceptable and extensible methods, due to advantages such as: fast operation, sensitive detection, low detection limit and no needs to (pre)treatment of samples [3].The objective of this study is to develop a sensitive and selective electrochemical method for detection of BPA. Therefore, a novel magnetic nanoparticle‐supported triethoxypropylthiole gold nanocomposite was successfully prepared by attaching Au NPs to functionalized Fe3O4 nanoparticles (Fe3O4@Au). The prepared nanocomposite was applied in fabrication of an electrochemical sensor (GCE/Fe3O4@Au). It was found the synthesized nanocomposite be highly efficient for the electrooxidation of BPA. Good linear range (0.005-120 μM) and low detection limit 1.62 nM (S/N=3) in determination of BPA were obtained. Moreover, the sensor was used at detection of BPA in some real samples.