Pharmaceutical evaluation of fertility drugs: quality and efficacy aspects

Safety and quality is one the most important domains of good medication practice (GMP). The outcomes of infertility treatment plans are strongly influenced by quality of drugs. Nowadays, the most of infertility management protocols employ biological products as the mainstay of treatment. The quality issue is very important in this drug category and can affect by several factors. Important features such as primary and higher order structures, including tertiary conformation, disulphide bonds, aggregate formation, glycopattern, and in-vitro and in-vivo bioactivity can lead to brand to brand or even batch to batch variation of biological products. It is clear that Physicians awareness about these characteristics can help them to select more appropriate drug products and so get the better results.

کلیدواژه ها:

fertility drugs ، quality ، biological products