The relation between dietary antioxidants and other nutrients; male fertility improvement viewpoints
محل انتشار: چهارمین کنگره بین المللی تولیدمثل
سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 406
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شناسه ملی سند علمی:
ISERB04_011
تاریخ نمایه سازی: 16 تیر 1397
چکیده مقاله:
It is argued that nutrition is recognized as a major non-genetic factor in fertility. On the other hand, oxidative stress is a major challenge in male infertility, and spermatozoa were the first cell type report to show sensitivity to oxidative damage. Therefore, the basic studies that focus on antioxidant supplementation as well as clinical results of antioxidant consumption confirmed the effective roles of antioxidants in reduction of reactive oxygen species (ROS) production, DNA fragmentation and improved male fertility. However, little information exists on the crosstalk between antioxidants and other nutrients in diet. For example, micro-mineral (selenium or zinc) levels in diet/serum may affect the vitamin E supplementation responses, or dietary polyunsaturated fatty acid concentration may affect antioxidant requirements and ROS production. Moreover, the required levels of some vitamins and micronutrients for animal models were updated by references. Indeed, harmful effects of nutrient’s overdose consumption may raise the possibility of ‘reductive stress’. It appears that the consumption of the antioxidant mixture is better than one source of antioxidantand dietary patterns such as Mediterranean diet could be recommended. On the whole, other diet ingredients in study designing as well as clinical advice should be take into account after the consumption of antioxidants for male fertility improvement.
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نویسندگان
AliReza Alizadeh
Department of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran