Lysozyme activity of grass carp (Ctenopharingodon idella) following exposure to sublethal concentrations oforganophosphate, diazinon

Lysozyme activity of grass carp (Ctenopharingodon idella) weighing 850 g were assessedfollowing exposing fish to various concentrations of diazinon at 1, 2 and 4mg/L provided as a bath for12 hours at 20–2”C. Compared with the control fish there was no significant difference in levels oflysozyme in tissues of spleen and kidney of experimental fish after one day post-exposing to thetoxicant (p>0.05), whilst lysozyme contents in sera of experimental fish were significantly lower thancontrol fish (p<0.05). After 7 day-post-exposing fish to toxicant, the lysozyme contents in both spleenand kidney of fish exposed to 2 and 4 mg/L of toxicant were significantly higher than control fish(p<0.05). Also, compared with control group, no significant difference was observed in lysozymecontent in sera and tissues of kidney and spleen of experimental fish 15, 30 and 45 days post-exposure(p>0.05). These results show that diazinon at sublethal concentrations stimulate some non-specificimmune defence mechanisms of grass carp through enhancing of lysozyme content in heamatopoeitictissues and blood serum. J.Vet.Res. 62,2:49-52,2007.

کلیدواژه ها:

Diazinon ، grass carp ، lysozyme