Antimicrobial Potential of Satureja Species: A Review of Bioactive Compounds and Molecular Mechanisms

Objective: The genus Satureja (Lamiaceae), commonly referred to as savory, has been traditionally valued for its medicinal properties, particularly its antimicrobial activity. Methodology: Methodology: In this review study, the key words satureja, antimicrobial resistance, antibiotics, carvacrol, thymol, multidrug-resistant were used to search for articles. Databases such as Google Scholar, SID, Magiran, PubMed, Scopus were used for searching. Results: Various species of Satureja are rich in bioactive compounds such as thymol, carvacrol, and terpenoids, which exhibit strong antibacterial, antifungal, and antiviral properties. These essential oils primarily act by disrupting bacterial cell membranes, inhibiting biofilm formation, and interfering with bacterial metabolism and DNA replication. This review critically examines the antimicrobial properties of nine Satureja species, focusing on their bioactive compounds, molecular mechanisms, and potential applications. Conclusion: Given the growing challenge of antimicrobial resistance (AMR), the therapeutic potential of Satureja is discussed in the context of alternative antimicrobial strategies and industrial applications.

کلیدواژه ها:

Satureja ، Antimicrobial resistance ، Antibiotics ، Carvacrol ، Thymol ، Multidrug-resistant