Modifying Chitosan with Arginine Peptides to Prepare Novel Nanocomposites forBiomedical Applications

In this work, chitosan was chemically modified via selective reactions with arginine to synthesize novelnanocomposites. Protection, activation, and coupling steps resulted in peptide bonds formation between thecomponents. Spectroscopic characterization verified successful derivatization. Decreasing crosslinker densityenhanced nanocomposite hydrophilicity and swelling capacity, tailoring properties for potential usage asantibacterial wound dressings.

کلیدواژه ها:

Chitosan ، Arginine ، Coupling reaction ، Nanocomposite