Changes of immunological factors in children with Obesity

Childhood obesity is a global health concern with significant implications for short-term and longtermhealth outcomes. This study aimed to investigate the association between lipid profile andobesity in children and explore the changes in immunological factors that occur in obese children.The study involved ۲۰ obese children and ۲۰ age-matched normal-weight control children. Bloodsamples were collected, and various immune factors were evaluated using Elisa kits assays. Theresults revealed significant changes in immune factors in obese children, including a weakenedinnate immune system, reduced cellular interactions, increased chronic inflammation, decreasedimmune response to vaccination, and an elevated risk of infections. These alterations inimmunological factors can contribute to obesity-related complications such as diabetes andcardiovascular diseases. Understanding these changes can improve strategies for managing andreducing childhood obesity, as well as aid in the development of tailored vaccines and vaccinationprograms for obese children. In conclusion, this study highlights the importance of understandingthe changes in immunological factors in obese children for diagnosing, preventing, and treatingobesity and its associated side effects. Further research in this area is warranted to developeffective interventions for addressing childhood obesity.

کلیدواژه ها:

obesity children ، immunological factors ، Elisa