Design at home Sperm Test Medical Device (SPOO) based on Machine Vision

Background and aims: Unfortunately, one in six couples is affected by infertility in the world.It is interesting to know that men and women have an equal share of this problem. Diagnosis isthe first step in solving this problem. Usually, couples go to the laboratory to take a test but thisprocess can be very embarrassing, expensive, time-consuming, and stressful. Among couplespresenting for infertility assessment, ۱۸% to ۲۷% of men will not be tested. We designed a selftestmedical device (SPOO) enabling men to test, analyze, and improve their sperm quality fromthe comfort of their own homes. SPOO is a smartphone-based home sperm test application thatevaluates sperm count, motility, and morphology and gives a complete fertility report that can beshared with a doctor. The aim of this paper is to introduce a smartphone-based Home Sperm Testaccurately and precisely measure sperm total motility, morphology and count versus the CASA,an automated laboratory semen analyzer.Method: ۳۵۰ human semen samples were tested by professionals at two sites utilizing the SPOOHome Sperm test kit. In parallel, the same samples were tested on the CASA automated semenanalyzer (VIDEO TEST SPERM ۳.۱). Samples were collected, liquefied, split and run in a blindedfashion. Professionals ran the SPOO test using the SPOO device on either a Galaxy Smartphonefollowing the SPOO app. SPOO uses the smartphone’s camera and light source and the SPOOClip (a mini-microscope) to capture a moving sperm video. Using proprietary algorithms, the appanalyzes the video and translates these movements into sperm count, motility and morphology.Results: The SPOO device demonstrated good correlation and good to moderate agreement withthe CASA for count and total motility parameters.Conclusion: The smartphone based device (SPOO) is affordable and convenient option for menwanting an answer about their fertility as soon as possible. The smartphone-based device has ahigh level of accuracy and precision when compared with the CASA. In the absence of a clear-cutevaluation and diagnosis of the male partner, the female partner may undergo unnecessary andunsuccessful medical interventions. This highlights the need for an at-home semen screening testthat is relevant, accurate, easy to use, and affordable. Thus, the SPOO can improve patient satisfactionand empowerment.

کلیدواژه ها:

artificial intelligence ، infertility ، sperm ، analyze