Interaction studies of anti-breast cancer agents derived from plants with human ۱۷-beta-hydroxysteroid dehydrogenase type ۱ using molecular docking approach

Here, we used molecular docking simulations to investigate the interaction mechanism of ۸ plant-derived compounds against ۱۷β-HSD type ۱. The results showed that all selected compounds were able to interact with the receptor, and Rosmanol and Resveratrol showed the highest and lowest binding affinity, respectively.

کلیدواژه ها:

Breast cancer ، Plant-derived compounds ، Human ۱۷-beta-hydroxysteroid dehydrogenase ، Molecular docking