The Damages made by Helicobacter Pylori on Parkinson and emerging role of nutrition in Parkinson’s Disease

Parkinson's disease is a widespread degenerative illness impacting the human central, Peripheral, and gastrointestinal nervous systems. The underlying pathological process slowly but relentlessly and involves multiple neuronal systems. The disease is the consequence of changes in the neuronal cytoskeleton developing in only a few susceptible types of nerve cells. the cardinal features of Parkinson disease are bradykineia, rigidity, tremor, and postural instability. There are a number of neurologic conditions that mimic the disease, making it difficult to diagnose in its early stages. Physicians who rarely diagnose Parkinson disease should refer patients suspected of having ti to plysicans with more experience in making the diagnosis, and should periodically reevaluate the accuracy of the diagnosis.: Several studies have shown associations between Parkinson Disease (PD) risk and individual foods and untrients with inconsistent results is now clear that genetic susceptibilty and enviroumental factors play a role in disease etiology and progression. Because envionmental factors are involved play a role in disease etiology and progression. Because environmental factors are involved with the majority of the cases of PD, it is important to understand the role nutrition plays in both neuroprotection and neurodegeneration. Helicobacter pylori has been implicated in the pathogenesis of Parkinson's disease (PD). Its eradication, in a randomized placebo-controlled trial, improved PD inactive Helicobacter species zoonsis might explain excess mortality from PD and non-Hodgkin lymphoma in livestock, but not arable, farmers. Indeed, Helicobacter is causaaly-associated with gastric lymphoma.

کلیدواژه ها:

Parkinson disease ، nutrition ، dietary pattern ، Helicobacter pylori ، interaction ، levodopa ، epidemiology