The effect of aerobic exercise on Hba۱c in people with non-alcoholic fatty liver )systematic review and meta-analysis)

Many studies have investigated the role of aerobic exercise in the factors associated with non-alcoholic fatty liver disease. Aerobic exercise along with lifestyle modification is one of the most important treatments for non-alcoholic fatty liver. Therefore, the aim of this study was to investigate the effect of aerobic exercise on blood glucose in people with non-alcoholic fatty liver.This research is a systematic review and meta-analysis that was conducted in ۱۳۹۹. For the present study, databases, ScienceDirect, PubMed, Scopus, science of Web, SID, Magiran and Google Scholar from ۱۳۸۱ to ۱۳۹۹, were searched along with keywords. After the initial screening, the full text of the articles was evaluated and the articles that met the inclusion criteria were analyzed. A total of ۱۲۰ articles were reviewed, of which ۱۷ articles met the criteria for entering the systematic review and meta-analysis. Accordingly, ۷۱۰ individuals with non-alcoholic fatty liver disease were divided into control and experimental groups of ۳۰۷ and ۴۰۳, respectively. The mean age of the subjects in the present study was ۱۰ ± ۵۲ years. The effects of the intervention were evaluated using the standardized difference (SMD) and the random effects model. Data were analyzed using effect size, bias and heterogeneity tests using STATA software.The results of meta-analysis showed that aerobic exercise significantly reduced Hba۱c (P= ۰.۰۰۱, SDM=-۰.۳۳, SE=۰.۱۲) ،in patients with non-alcoholic fatty liver.Aerobic exercise improves Hba۱c index levels in people with non-alcoholic fatty liver, so it can be recommended that people with fatty liver to improve their health and lifestyle should be regular and long-term aerobic exercise Use.

کلیدواژه ها:

non-alcoholic fatty liver disease ، aerobic exercise ، HbA۱c