Effect of a ۸-Week High Intensity Aerobic Exercise Training on Appetite-Regulating Hormones in Obese Adolescents

Background. In obese adolescents similar studies on the influence of variations in exercise intensity on eating behavior, food intake and appetite-regulating hormones are sparse. The orexigenic and anorexigenic hormones such as leptin and agouti-related protein (AGRP) respectively, appear to play important roles in the regulation of appetite. Adolescents obesity is one of the most severe public challenges in the ۲۱st century. However, Little information is available about the effects of high intensity aerobic exercise training (HIT) and arginine supplementation on appetite regulating hormones in obese adolescents. Purpose. The purpose of this study was to investigated the effect of ۸ weeks of HIT and supplementation of arginine on leptin and AGRP in obese adolescent boys. Methodology. In isoenergetic conditions, ۲۰ obese adolescents aged ۱۰ to ۱۵ years old and body mass index of (BMI) ۲۹.۴۴ ± ۲۹.۴ Kg were randomly divided into two groups including: ۱) HIT and placebo (C, n=۱۰) and HIT with supplementation of arginine (T, n=۱۰). Before and ۴۸ hours after the last exercise session, serum levels of variable were measured by ELISA method. ANCOVA and paired sample T test were used in order to analyze the differences between intra-and intergroup, respectively. Results. The results showed that despite significant reduction in body weight and body fat present among and between groups (p≤۰.۰۵), however, there was no significant difference between leptin and AGRP compared to baseline levels among and between groups (P ≥۰.۰۵). Conclusion. Eight weeks of arginine supplementation and HIT training compared with Hit training alone, led to more reduction in weight and body fat percent in obese adolescent but no effect on appetite regulatory hormones.

کلیدواژه ها:

High Intensity Aerobic Exercise Training ، Obesity Appetite-Regulating Hormones