Complete genome sequence of a subgenotype XXI.۱.۱ pigeon paramyxovirus type ۱ virus (PPMV-۱) isolated from Iran in ۲۰۱۸ and phylogenetic analysis of apossible novel, but unassigned, PPMV-۱ group isolated in ۲۰۱۴

Newcastle disease (ND) is one of the most important infectious viral diseases in avian species. Recently, several ND outbreaks in pigeons caused by pigeon paramyxovirus serotype-۱ (PPMV-۱) have been reported from Iran. In addition, a complete genomedata of Iranian PPMV-۱ strains is notavailable. In the present study, a PPMV-۱, named Avian avulavirus ۱/pigeon/Iran/UT-EGV/۲۰۱۸, isolated from an infected pigeon, was subjected to whole-genome sequencing. The phylogenetic analysis based on the F gene sequence revealed the isolate belongs to XXI.۱.۱ subgenotype. To ourknowledge, our study is the first to publish the complete genome of a PPMV-۱ from Iran. According to BLAST results, the whole genome of UT-EGV had high homology with some Russian, Egyptian and Ukrainian strains. Additionally, we conducted a phylogenetic analysis on five PPMV-۱ that we isolated in ۲۰۱۴ to find that they may belong to a completely unreported subgenotype (۶% distance when compared as a group).

کلیدواژه ها:

pigeon paramyxovirus serotype-۱ (PPMV-۱) ، complete genome ، fusion gene ، phylogenetic Study ، epidemiology ، Iran