Medical Devices and Artificial Organs

Background and objective: One important goal for Regenerative Medicine is to develop and define methods that will maintain, improve or even restore the function of diseased organs. The growing need for these technologies is substantial.Search method: In the context of this overview, 14 articles were used between the years 2010 through the end of 2018 using the Keywords of PubMed, Google scholar search engines.Results: Improved health care has resulted in an increased life span for the general population and, when coupled with a growing shortage of donor organs, makes it clear that organ assistance and substitution devices will play a larger role in managing patients with end-stage disease by providing a bridge to recovery or transplantation. The good news is that the field of medical device and artificial organ development is redefining what is believed to be possible for augmenting or replacing organ function. Once constructed only of synthetic components, these devices may now be either fully artificial or bio artificial- so-called “biohybrid organs” – a combination of biologic and synthetic components, often incorporating multiple technologies involving sensors, new biomaterials, and innovative delivery systems.Conclusion: Some devices can provide assistance while new therapies incorporating stem cells, gene therapy, or engineered tissues are employed to repair or replace the damaged organ. Until these interesting therapies can be introduced and generated, medical devices must play a crucial role in facilitating organ regenerating and, maybe, organ salvage through natural repair process. If organ regeneration is impossible, artificial organs can provide a substitute for natural organs.

کلیدواژه ها:

Medical devices ، Artificial organs ، Tissue regeneration