THE ANALGESIC EFFECT OF INTRANASAL KETAMINE AND IV MORPHINE IN PATIENTS WITH FLANK PAIN (RENAL COLIC) IN THE EMERGENCY DEPARTMENT: A CLINICAL TRIAL STUDY

سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 494

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شناسه ملی سند علمی:

EMERGENCYMED14_056

تاریخ نمایه سازی: 26 بهمن 1398

چکیده مقاله:

Background and Aim : Renal colic is the most common clinical manifestation of urinary stones.This study was aimed to compare the effect of intranasal ketamine vs. intravenous morphine onrenal colic.Methods : In this clinical trial study, 100 patients with renal colic were entered into the study andrandomly divided into two groups. Patients in treatment group received intranasal ketamine (1.5mg/kg), and the other group was given intravenous morphine (0.1 mg/kg). The pain was measuredat 0, 5, 15, 30 and 60 minutes after medication administration.Results : In this study, 32% of patients were female and 68% were male. Also, the differencebetween the initial pain with pain at all subsequent times in the two groups were significant (P<0.001). The duration of the ketamine effect to control pain was longer, but with the administra t ionof morphine, a faster effect on pain relief was achieved.Conclusion : Low-dose ketamine is considered as an analgesic with low side effects, with simpleand uncomplicated usage that reduces the risk of the needle stick in pre-hospital conditions. Onthe other hand, IV morphine has a faster effect, therefore its use in patients with severe pain shouldbe given priority.

نویسندگان

Abdolghader Pakniyat

Emergency Medicine Department, Kowsar Hospital, Kurdistan University of Medical Sciences, Sanandaj, Iran

Ali Abdolrazaghnejad

Department of Emergency Medicine, Khatam-Al-Anbia Hospital, Zahedan University of Medical Sciences, Zahedan, Iran

Ali Rajabpour-Sanati

Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran

Hojjat Rastegari Najafabadi

Department of Emergency Medicine, Khatam-Al-Anbia Hospital, Zahedan University of Medical Sciences, Zahedan, Iran

Maryam Ziaei

Department of Emergency Medicine, Khatam-Al-Anbia Hospital, Zahedan University of Medical Sciences, Zahedan, Iran