Speech and Language Impairments as the Primary Presentation of Creutzfeldt Jakob Disease

Creutzfeldt–Jakob disease (CJD) is a neurodegenerative disorder and caused by a proteinaceous infectious agent called a prion resultsin the accumulation of prion protein (PrPsc) in the brain. Reports of this disease include people of every two gender and are more frequent in the fifth and sixth decades of life. Given that the population goes to aging, the study of the diseases of this period finds special significance and given the progressive nature of the CJD disease, attention to symptoms is very important for early diagnosis and early treatment. Rapidly progressing dementia, ataxia, muscle tone alterations, and myoclonus are the manifestations of this disease, however, often CJD is associated with atypical clinical presentation and/ or inconclusive initial workup. Some studies reported speech and language signs in CJD patients and has been found one of the initial manifestation of CJD was language and speech difficulties that progressed worse. Linguistic symptoms in these patients include some types of aphasia, especially progressive aphasia over time, and dysarthria, apraxia, and stuttering are mentioned for speech symptoms. Conclusion: Speech and language problems in patients with CJD are important from this