7α–Acetoxyroyleanone Terpenoid Extracted from Salvia Virgatae Collected in Northern Iran

Salvia extracts have been used widely for various medicinal applications. The Most biologicalactivity is dedicated to abietane diterpenoids, as a major content of extract. This terpenoid hasantibacterial, antifungal, anti-Alzheimer, insecticide, cardiovascular disease Treatment Properties[1]. Seventeen species of Salvia are endemic in flora of Iran. Salvia Virgata is a memberof Iranian endemic species on whose content there is no phytochemical studies [2]. Isolationand purification of compounds was done using column chromatography technique. Finally, 25major fraction were selected after comparing thin layer chromatography. Crystalline sampleswere recrystallized with different solvents. A pure substance was identified using 1H-NMR,13C-NMR and Mass spectra. An abietane diterpenoid (7a -acetoxyroyleanone) was newlyidentified for the first time in this specie (Fig. 1).Diversity of flavonoid and terpenoid compounds in genus Salvia, along with little phytochemicalresearches, promises the potential of discovery of new medicinal phytochemicals in thisspecie.