Evaluation of drug susceptibility of oral strains of Candida albicans in HIV+ patients

سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 443

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شناسه ملی سند علمی:

CMTS02_242

تاریخ نمایه سازی: 29 تیر 1398

چکیده مقاله:

The objective of this study was to investigate the antifungal susceptibility of oral Candida albicans (C. albicans) strains isolated from HIV+ patients. A total of 50 C. albicans isolates were cultured on Sabouraud glucose agar (SGA) containing chloramohenicol. The antifungal susceptibility of C. albicans against fluconazole, clotrimazole, nystatin, amphotericin B, ketoconazole and flucytosine was assessed using disc diffusion method. The inhibition zones ranged from 4±1.8 to 40±3.8 mm for fluconazole, 7±1.0 to 37±1.8 mm for ketoconazole, 14±0.8 to24±0.8 mm for amphotericin B, 25±0.0 to 33±0.0 mm for nystatin and 7±4.2 to 40±0.0 mm for clotrimazole. We concluded that C. albicans strains from HIV+ patients were resistant to flucytosin and susceptible to nystatin.

نویسندگان

Hojjatollah Shokri

Associate professor, Faculty of Veterinary Medicine, Amol University of Special Modern Technologies, Amol, Iran.

Ali Reza Khosravi

Full professor, Mycology Research Center, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.

Iradj Ashrafi Tamai

Assistant professor, Department of Microbiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.