Study of Aqueous Biphasic sSystems Composed of Biocompatible Cholinium Aminoate Ionic Liquids as Novel Extractants and Polyethylene Glycol Di-Methyl Ether for Separation of Bovine Serum Albumin (BSA)
محل انتشار: بیست و یکمین کنفرانس شیمی فیزیک انجمن شیمی ایران
سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 218
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شناسه ملی سند علمی:
ISPTC21_225
تاریخ نمایه سازی: 30 دی 1397
چکیده مقاله:
Aqueous biphasic systems, ABSs, are known as interesting media for the separation andpurification of proteins [1-4]. From this viewpoint, the ambition of this work is investigatingability of cholinium aminoate ([Ch][AA]) as novel, low toxic and high biodegradable ionicliquids including of cholinium glycinate, cholinium prolinate and cholinium valinate for inducingABSs with polyethylene glycol di-methyl ether, PEGDME, and then evaluating theirperformances for partitioning of bovine serum albumin, BSA, as a model protein. For achievingthis purpose, binodal curves and tie-lines were experimentally measured at 298.15 K for threeABSs. Two empirical equations including Merchuk equation were applied in order to representthe binodal data. Tie-line were correlated with two versions of NRTL models (i.e. e-NRTL andm-NRTL). In addition, the partition behavior of BSA was studied by measuring of partitioncoefficient and extraction efficiency in mentioned systems.
کلیدواژه ها:
نویسندگان
Parisa Jafari
Physical Chemistry Department, University of Tabriz, Tabriz, Iran,
Mohammad Taghi Zafarani-Moattar
Physical Chemistry Department, Faculty of Chemistry, University of Tabriz, Tabriz
Hemayat Shekaari
Physical Chemistry Department, Faculty of Chemistry, University of Tabriz, Tabriz