The effect of pH on the synthesis of MFI-type drug delivery systems

Over the past decades, much attention has been devoted to the design of efficient drug delivery systems (DDSs). In this way, zeolites and zeolite composites have been considered as potential DDSs [1, 2]. The drug loading capacity of zeolites can be controlled by variations in the Si/Al ratio of zeolite [2] or by incorporation of heteroatoms into the zeolites framework [3]. The incorporation of heteroatoms into the framework of zeolites has been developed as a suitable method for tailoring the physicochemical properties of zeolites [4]. For an efficient incorporation of heteroatoms into the framework of zeolite, the precise control of synthesis parameters is inevitable.In this work, we report the effect of synthesis gel pH on the crystallization and morphology of MFI-type borosilicate ([B]-MFI) zeolites. We also consider the efficiency of prepared zeolites as DDSs