Magnetic nanoparticles and their application in drug delivery
سال انتشار: 1396
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 460
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شناسه ملی سند علمی:
CHCONF04_402
تاریخ نمایه سازی: 8 آذر 1396
چکیده مقاله:
The blood–brain barrier (BBB) represents an insurmountable obstacle for a large number of drugs,including antibiotics, antineoplastic agents, and a variety of central nervous system (CNS)-active drugs,especially neuropeptides. One of the possibilities to overcome this barrier is a drug delivery to the brainusing nanoparticles. The application of nanotechnology for cancer therapy has received considerableattention in recent years. Cancer nanotechnology (an interdisciplinary area of research in science,engineering and medicine) is an upcoming field with extensive applications. Among the broad spectrum ofNano scale materials being investigated for biomedical use, magnetic nanoparticles (MNPs) have gainedsignificant attention due to their intrinsic magnetic properties, which enable tracking through the radiologycornerstone, magnetic resonance (MR) imaging. This class of NPs includes metallic, bimetallic iron oxidesuper paramagnetic iron oxide nanoparticles (SPIONs). In this review Article, the intrinsic properties ofmagnetic NPs were exploiting to obtain medical breakthroughs in diagnosis, and drug delivery. Perhapsthe most promising applications relate to the diagnosis and treatment of cancer. It provides a uniqueapproach and comprehensive technology against cancer through early diagnosis, prediction, prevention,personalized therapy and medicine. Target-specific drug therapy and methods for early diagnosis ofpathologies are the priority research areas in which nanotechnology would play a vital part.
کلیدواژه ها:
نویسندگان
Mohsen Mataji
Ph.D Student in chemical engineering, Islamic Azad University, Ayatollah Amoli Branch, Amol, IranMazandaran gas company, Sari, Iran
Arezou Ghadi
A Faculty Member of the Department of Chemical Engineering, Islamic Azad University, Ayatollah Amoli Branch,Amol, Iran
Mehdi Bazyari
Ph.D Student in chemical engineering, Islamic Azad University, Ayatollah Amoli Branch, Amol, Iran HSE Expert, Pars Oil & Gas Company, Asaluyeh, Iran
Yaghub Esfandyari
Ph.D Student in chemical engineering, Islamic Azad University, Ayatollah Amoli Branch, Amol, Iran