Effects of berberine dietary supplementation on blood parameters fattening lambs

This study evaluated the effects of berberine (BBR) supplementation on blood parameters in fattening lambs. Twenty-one male Baluchi lambs (three months old; ۲۶.۵ ± ۲.۱۰ kg body weight, mean ± SD) were randomly allocated to one of three treatments (n = ۷ per treatment): ۰ g/d BBR (Ctrl), ۰.۵ g/d BBR (BBRO.۵), or ۱.۰ g/d BBR (BBRI). Following a ۱۴-day adaptation period, lambs received the experimental treatments for ۶۰ days. The basal diet, formulated with a ۳۰:۷۰ forage-to-concentrate ratio, met or exceeded the nutrient requirements of finishing lambs. Animals were offered a total mixed ration twice daily (۰۶:۰۰ and ۱۴:۰۰ h) for ad libitum intake and had unrestricted access to water. Blood samples were collected on days ۰, ۳۰, and ۶۰. The results showed that lambs supplemented with ۱.۰ g/d BBR had the lowest plasma triglyceride (TG; p = ۰.۰۳۳) and cholesterol (CHOL; p = ۰.۰۴۶) concentrations, followed by those receiving ۰.۵ g/d BBR; both treatment groups had lower values than the control group. In addition, aspartate aminotransferase (AST; p = ۰.۰۴۸) and alkaline phosphatase (ALP; p = ۰.۰۳۱) levels were reduced in the BBRI group compared with the control. Overall, BBR supplementation improved several blood biochemical parameters in fattening lambs.

کلیدواژه ها:

Berberine ، Blood parameters ، Lambs ، Supplementation