Reconsidering the Metabolic Effects of TBHQ: An Overlooked Interaction between Dietary Antioxidants, Lipid Metabolism, and Inflammatory Pathways

In recent years, there has been increasing attention on the role of dietary antioxidants in the prevention and modulation of metabolic disorders, particularly metabolic syndrome (MetS). While natural antioxidants have consistently demonstrated beneficial metabolic effects, not much is known about the long-term metabolic consequences of synthetic antioxidants used in food processing. Among these, tertiary butylhydroquinone (TBHQ) is widely incorporated into edible oils to prevent lipid oxidation and prolong shelf life. Despite its technological advantages, the biological relevance of TBHQ exposure to metabolic health remains poorly characterized.

کلیدواژه ها:

TBHQ ، dietary antioxidants ، lipid metabolism ، inflammatory pathways ، metabolic syndrome ، oxidative stress