A novel voltammetric sensor for Tarceva determination using Graphene oxide nanoribbon/Ni-Metal organic framework modified electrode

In this research the goal is to construct Graphene oxide nanoribbon/Nickle metal-organic frameworks modified glassy carbon electrode for sensitive electrochemical determination of Tarceva. The modifier was prepared via one-step solvothermal method. Characterization of modified electrode surface was investigated by scanning electron microscopy and FT-IR. The synthesized nanoparticles significantly increase the oxidation current of Tarceva which lead to its trace-level quantification. The proposed method had a linear dynamic range from ۰.۷ to ۵۰.۰ μmol L-۱ with detection limit of ۰.۱ μmol L-۱. The modified electrodes were successfully applied for the determination of Tarceva in tablets.

کلیدواژه ها:

Modified electrode ، Tarceva ، Graphene nanoribbon/Nickel-BTC metal-organic frameworks ، Electrochemical determination