A Cost-effective Synthesis of High Pure Ticagrelor, an Anti-platelet Drug

سال انتشار: 1401
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 156

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شناسه ملی سند علمی:

ICCNRT05_044

تاریخ نمایه سازی: 8 آذر 1401

چکیده مقاله:

Coronary heart disease (CHD) is the most common cause of morbidity and mortality globally based on the world health organization (WHO) reports. Ticagrelor, a cyclopentyltriazolo-pyrimidine, is known as a new chemical class of P۲Y۱۲ antagonist which used in the wide spectrum of Coronary heart disease (CHD). In this article the high pure Ticagrelor drug was synthesized through efficient and cost-effective process. Final crystallization was done in Ethyl acetate solvent to attain desired high pure Form-II of Ticagrelor.

کلیدواژه ها:

Ticagrelor ، P۲Y۱۲ antagonist ، Coronary heart disease (CHD) ، Anti-platelet Drug

نویسندگان

Adileh Ayati

Antibiotic Sazi Iran Company (ASICO)th Km of Khazarabbad Road- Sari-IRAN

Marzieh Sadatshahabi

Antibiotic Sazi Iran Company (ASICO)th Km of Khazarabbad Road- Sari-IRAN

Ali Setayesh

Antibiotic Sazi Iran Company (ASICO)th Km of Khazarabbad Road- Sari-IRAN

Nader Teymoori

Antibiotic Sazi Iran Company (ASICO)th Km of Khazarabbad Road- Sari-IRAN