A Cost-effective Synthesis of High Pure Ticagrelor, an Anti-platelet Drug
سال انتشار: 1401
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 215
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شناسه ملی سند علمی:
ICCNRT05_044
تاریخ نمایه سازی: 8 آذر 1401
چکیده مقاله:
Coronary heart disease (CHD) is the most common cause of morbidity and mortality globally based on the world health organization (WHO) reports. Ticagrelor, a cyclopentyltriazolo-pyrimidine, is known as a new chemical class of P۲Y۱۲ antagonist which used in the wide spectrum of Coronary heart disease (CHD). In this article the high pure Ticagrelor drug was synthesized through efficient and cost-effective process. Final crystallization was done in Ethyl acetate solvent to attain desired high pure Form-II of Ticagrelor.
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نویسندگان
Adileh Ayati
Antibiotic Sazi Iran Company (ASICO)th Km of Khazarabbad Road- Sari-IRAN
Marzieh Sadatshahabi
Antibiotic Sazi Iran Company (ASICO)th Km of Khazarabbad Road- Sari-IRAN
Ali Setayesh
Antibiotic Sazi Iran Company (ASICO)th Km of Khazarabbad Road- Sari-IRAN
Nader Teymoori
Antibiotic Sazi Iran Company (ASICO)th Km of Khazarabbad Road- Sari-IRAN