Comparison Specificity of Invasive and Serologic Methods inthe Diagnosis of Helicobacter pylori in Khorrmabad City, Iran

Background and Aim : Helicobacter pylori is a gram-negative bacterium that is the main etiologyof peptic ulcers and chronic gastritis. The prevalence of this bacteria is typically high in developingcountries. This study aimed to compare the specificity of invasive pathological and serologicmethods in diagnosing Helicobacter pylori in hospitals in Khorramabad city.Methods : This study was performed on ۱۰۰ samples of Shohadaye Ashayer & Shahid Rahimihospitals in Khorramabad city, Iran. The gastric antrum and duodenal biopsies were done to detectH. pylori by pathological methods and determine if the Antibody was done by the ELISA method.Results : The number of positive results obtained in this study was ۶۰% by pathology and ۳۳% byserology. The number of women with infections was higher than that of men. The highest rate ofinfection was between the ages of ۳۰ and ۴۰ yearsConclusion : In this study, the pathology method was more accurate than the serologic method indetecting Helicobacter pylori H. pylori infection. So, antibody titration alone is not sufficient fordefinitive diagnosis and requires invasive pathological methods such as biopsy

کلیدواژه ها:

Helicobacter pylori ، invasive pathology ، noninvasive ، serology