Evaluating factors associated with uncontrolled hypertension: Isfahan cohort study, Iran

BACKGROUND: Hypertension (HTN) considers as one of the most common risk factors, which potentially raises the risk of cardiovascular disease. Regarding high prevalence of HTN among Iranian population this study designed to examine a range of socio-demographic and clinical variables to determine the association with failure to achieve blood pressure control in a cohort of hypertensive subjects. METHODS: This retrospective cohort study is a part of Isfahan cohort study which carried out on adults aged ۳۵ years old or more. Subjects with confirmed HTN entered in this sub-study. For all subjects questionnaire included socio-demographic characteristics, clinical data and lifestyle behavior completed by trained nurses. Uncontrolled HTN was defined as systolic and diastolic blood pressure more than ۱۴۰/۹۰ in the presence or absent of pharmacological treatment. RESULTS: The prevalence of uncontrolled men was significantly higher than controlled in both ۲۰۰۱ and ۲۰۰۷ (P < ۰.۰۰۱). A significant association was found between sex and control of blood pressure: compared with women, being men [odds ratio (OR) = ۲.۳۱; ۹۵ % confidence interval (CI) = ۱.۶۴-۳.۲۴] was significantly associated with uncontrolled HTN in ۲۰۰۱ and (OR = ۲.۳۸; ۹۵% CI = ۱.۷۸-۳.۱۸). Among lifestyle behaviors, tendency for more consumption of salty foods increased the risk of uncontrolled HTN in ۲۰۰۱ by ۱.۷۳ times [OR = ۱.۷۳, ۹۵% CI = ۱.۲۰-۲.۵۰, (P = ۰.۰۰۳)]. Patients who were naive to mono-therapy without considering the type of antihypertensive drug were found to be associated with uncontrolled blood pressure (OR = ۰.۱۴; ۹۵ % CI =۰.۱-۰.۲). CONCLUSION: Uncontrolled HTN was sex, marital status, diabetes, tendency to salty foods and medication adherence. Assessment of them presence of these risk factors is warranted to recommend an aggressive HTN management with the goal of reducing excessive risk of cardiovascular events caused by uncontrolled HTN. 

کلیدواژه ها:

Prevalence ، Hypertension ، Uncontrolled ، Risk Factors