Antimicrobial activity of various extracts of Sargassum glaucescens on the antibiotic resistant organisms

The antimicrobial activity of brown alga methanol, ethyl acetate, hexane, and chloroform extracts on gram positive and gram negative bacteria, and fungi was evaluated by using nutrient broth macro dilution test. Sargassum glaucescense was collected around the coastal area of Chabahar (south of Iran) the protected marine area of the Oman Sea in April and May ۲۰۱۵. Six pathogenic organisms including; Enterococcus faecium ATCC ۵۱۲۹۹, Streptococcus mutans ATCC ۳۵۶۶۸, Shigella boydii ATCC ۲۵۹۲۳, Pseudomonas aeruginosa ATCC ۲۷۸۵۳, Klebsiella pneumoniae ATCC ۱۳۸۸۳, Salmonella enteritidi PTCC, ۱۷۰۹, Candida albicans ATCC ۱۰۲۳۱ and Aspergillus fumigatus PTCC ۵۰۰۹ were investigated by the broth dilution method. Methanolic extract of six strains showed good activity amongst eight strains. Hexane extract, after methanolic extract has a good effect on the antimicrobial activity against five strains. All bacterial strains in this survey showed resistance against ethyl acetate and chloroformic extracts. S. glaucescens using four various  solutions extracts against eight different human pathogens showed an important antimicrobial and antifungal activity. However, more investigation has to be done on separation, purification and detection of the active ingredients in order to recognize their antifungal and antifungal activity.

کلیدواژه ها:

Antimicrobial activity ، Sargassum glaucescens ، Bacteria ، Fungi ، Oman Sea.