Investigation of multicolor carbon dots stability for cellular applications

Recently, carbon dots (CDs) have received much attention owing to their advantages such as low toxicity, the ability of surface functionalization, high stability, and simple and cost-effective synthesis. Another feature of CDs is the ability of CDs synthesis from some natural or green sources such as fruits, vegetables, and etc. that this feature of CDs makes them biodegradable particles with low toxicity. Another interesting property of CDs is ability of multicolor CDs synthesis with concentration variation or surface functionalization that this property of CDs, recently receives much focus in cellular studies. In this research, we synthesized multicolor CDs from a green source by hydrothermal method. Then, after characterization, the optical properties of the appropriate concentration of prepared CDs were investigated. The fluorescence intensity spectra of multicolor CDs were measured during four different periods of time, including ۰, ۳, ۶, and ۱۲ months. It should be mentioned that, by decreasing CDs concentrations, the color of CDs changed from green to blue that these results were confirmed by fluorescence spectrophotometer. Besides, fluorescence spectroscopy and the quantum yield of synthesized multicolor CDs can indicate the high stability after a year and this photostability feature of nano particles is of crucial importance in different fields of cellular studies such as drug delivery, biomarkers, imaging in targeted cell lines or tissues.

کلیدواژه ها:

nanoparticles ، cell imaging ، fluorescence particles ، biodegradable