Assessment of nanosilver toxicity in the blood of goldfish (Carassius auratus L.)

سال انتشار: 1399
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 163

نسخه کامل این مقاله ارائه نشده است و در دسترس نمی باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

BIOCONF21_0657

تاریخ نمایه سازی: 7 شهریور 1400

چکیده مقاله:

Nanotechnology and nanoparticles are increasingly recognized for their potential applications in aerospace engineering, nano-electronics, environmental remediation, medical healthcare and consumer products. Nanosilver (AgNPs) is one of the most commonly used nanomaterials because of its strong antibacterial properties. Due to its small particle size and specific surface area, AgNPs may end up in aquatic ecosystems posing a huge threat to aquatic organisms. In the current study, our goal was to assess the AgNPs toxicity in goldfish (Carassius auratus L.) blood. AgNPs (۱۰, ۳۰ & ۵۰ ppm) were added to ۵۰L plastic tanks (n=۱۰) and kept under lab standard conditions. Following ۷ and ۱۴ days, blood samples were collected from caudal veins. Then, in blood sera, hepatic necrosis biomarkers (ALT&AST), glutathione S-transferase (GST) activity as an antioxidant enzyme and also lysozyme activity were measured and compared to control ones. Resulting data showed that AgNPs treatments caused an marked elevation (p<۰.۰۵) in GST activity confirming induction of oxidative stress via free radical production. Meanwhile, an increase (p<۰.۰۵) in the ALT&AST levels indicating a severe hepatic necrosis in fishes. An elevation in lysozyme activity (p<۰.۰۵) shows an antigenic role for AgNPs which could induce the non-specific immunity in the goldfish blood samples. Collectively, AgNP may exert toxicity in aquatics via inducing a severe oxidative stress and hepatic necrosis as an antigenic particle.

نویسندگان

Mehran Arabi

Animal Sciences group, Faculty of Basic Sciences, Shahrekord University, Iran.

Farzaneh Ahmadi Farsani

Animal Sciences group, Faculty of Basic Sciences, Shahrekord University, Iran.

Shervin Tousinia

Animal Sciences group, Faculty of Basic Sciences, Shahrekord University, Iran.