Background and Aim : The
Brucella abortus (IRIBA) vaccine is currently used for calves brucellosis in Iran. Currently, the production of the vaccine is by traditional cultivation on a solid medium in RVSRI, but the fermentation production using a liquid culture medium is under development. An ideal live vaccine should have long-term protection period against infection and abortion at any age of cattle. However, the main barriers to improving quality and increasing production capacity are traditional production process as well as supplying necessary raw materials for vaccine production and lack of standard reference seed preparation from OIE centers. In order to obtain better performance of the production of brucellosis vaccines in cattle to enable the improvement of disease surveillance and reporting in Iran, a
SWOT analysis was carried out for the current vaccine production to identify weaknesses and areas that could be improved to enhance disease surveillance and reporting structures.Methods : A systematic review was carried out to obtain data on the strengths, the weaknesses, the opportunities and threats to IRIBA vaccine production, using a Matrix Preparation (SWOT) of internal and external influence factors. The identified factors were then allocated to each parameter as they were determined, and discussed.Results : The results of the
SWOT analysis a based on the situational assessment of the IRIBA vaccine production, the following gaps and challenges have been identified: Persons with experience are available for training to new generations of vaccine and build capacity for improved the vaccine production and management. The infrastructure required for implementing production line and programs for IRIBA vaccine is weak, especially during times of production and deployment. Greater involvement of expert people is needed in the creation of activities and renovation of the IRIBA vaccine production line.Conclusion : The factors identified in this study could be effective and improvement through capacity building training, survey development and the use of this training in the production of the brucellosis vaccine in Iran. However, this concept provides a sustained groundbreaking platform for a real change in the vaccine production paradigm towards the development of successful measures to contain the Brucella vaccine dilemma.