New protocol to the synthesis of spiro dihydropyrrole-oxindole derivatives
سال انتشار: 1399
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 271
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شناسه ملی سند علمی:
IRCCE08_003
تاریخ نمایه سازی: 18 اردیبهشت 1400
چکیده مقاله:
A novel approach for the synthesis of spiro [indoline-۳,۲'-pyrrole] derivatives through a three-component reaction of isatin-based ketimines, pyridinium salts, and alkynes in the presence of DABCO under low power microwave irradiation is developed. The products were obtained in ۷۰-۹۵% yields in ۳-۱۵ mins. The advantages of this method consist of environmentally friendly reaction conditions, short reaction times, and good to excellent yields.
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نویسندگان
Mohadeseh Verdian
Department of Chemistry, University of Mazandaran, Babolsar, Iran
Robabeh Baharfar
Department of Chemistry, University of Mazandaran, Babolsar, Iran
Saadieh Mohajer Darabi
Department of Chemistry, University of Mazandaran, Babolsar, Iran