New protocol to the synthesis of spiro dihydropyrrole-oxindole derivatives
عنوان مقاله: New protocol to the synthesis of spiro dihydropyrrole-oxindole derivatives
شناسه ملی مقاله: IRCCE08_003
منتشر شده در هشتمین کنفرانس بین المللی شیمی ، مهندسی شیمی و نفت در سال 1399
شناسه ملی مقاله: IRCCE08_003
منتشر شده در هشتمین کنفرانس بین المللی شیمی ، مهندسی شیمی و نفت در سال 1399
مشخصات نویسندگان مقاله:
Mohadeseh Verdian - Department of Chemistry, University of Mazandaran, Babolsar, Iran
Robabeh Baharfar - Department of Chemistry, University of Mazandaran, Babolsar, Iran
Saadieh Mohajer Darabi - Department of Chemistry, University of Mazandaran, Babolsar, Iran
خلاصه مقاله:
Mohadeseh Verdian - Department of Chemistry, University of Mazandaran, Babolsar, Iran
Robabeh Baharfar - Department of Chemistry, University of Mazandaran, Babolsar, Iran
Saadieh Mohajer Darabi - Department of Chemistry, University of Mazandaran, Babolsar, Iran
A novel approach for the synthesis of spiro [indoline-۳,۲'-pyrrole] derivatives through a three-component reaction of isatin-based ketimines, pyridinium salts, and alkynes in the presence of DABCO under low power microwave irradiation is developed. The products were obtained in ۷۰-۹۵% yields in ۳-۱۵ mins. The advantages of this method consist of environmentally friendly reaction conditions, short reaction times, and good to excellent yields.
کلمات کلیدی: spiro [indoline-۳,۲'-pyrrole], three-component reaction, isatin-based ketimines, microwave, pyridinium salts
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1197795/