The synthesis of Spiro-oxindole compounds by 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione, Pyrazole and Pyrazolone

سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 136

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شناسه ملی سند علمی:

ISOC27_295

تاریخ نمایه سازی: 19 اسفند 1399

چکیده مقاله:

Recently, we have described a simple and straightforward preparation of novel spiro-oxindole by tricyclic and four cyclic Isatin.1-5 Interest to the synthesis of novel spiro compounds, we have now demonstrated the p-TSA catalyzed and green synthesis of novel spiro-oxindole 4 by condensations of variously 5-aminopyrazole 2 with Ethyl acetoacetate 3 and 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione 1 (scheme 1).In the other case of our work, we examined the reaction of 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione 1, 3-methylpyrazol-5-one 5 and Ethyl acetoacetate 3 in H2O (scheme 2).The desired products were produced in good yields and their structures were determined on the basis of their spectroscopic analysis data.

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نویسندگان

Hadi Zare Fazlelahi

Department of Organic Chemistry, Faculty of Chemistry, Urmia University, Urmia, Iran

Peyman Najafi Moghadam

Department of Organic Chemistry, Faculty of Chemistry, Urmia University, Urmia, Iran

Mohammad Mehdi Baradarani

Department of Organic Chemistry, Faculty of Chemistry, Urmia University, Urmia, Iran