HN-01190273_Impacts of Dietary Patterns on Dietary Inflammatory Indices and Systematic Inflammation in Obese Cases

Introduction: The dietary inflammatory index (DII®) is a novel scoring algorithm that provides an estimate of inflammatory potential of diet based on overall inflammatory properties of dietary constituents. In general inflammation is considered a key mechanism leading to obesity. Few studies have examined the contribution of major dietary patterns to inflammatory potential of diet. The present study aimed to examine the associations of different dietary patterns with dietary inflammatory index (DII), systemic inflammation,) in the apparently healthy obese.Methods: In this cross-sectional study, 151 abdominally obese subjects were recruited in the Northwest of Iran. Basic dietary intake, anthropometric indices, and physical activity (PA) were assessed. DII scores were calculated based on dietary intake, using a validated 168-item food frequency questionnaire (FFQ). Three dietary patterns were identified, using principal component analysis. Basal blood samples were collected to determine the biochemical parameters. Linear regression test with adjusted beta estimates was applied for data analysis.Results: Three dietary patterns were identified as Healthy, Western, and Traditional. Body mass index (BMI) (p<0.01) and fat mass (p<0.001) were positively associated with Western dietary pattern. Conversely, serum lipopolysaccharide binding protein (LBP) (b=-0.18, p<0.04) was negatively associated with Healthy dietary pattern, after controlling for confounders. A dietary pattern labeled as Traditional pattern was found to be negatively related to DII (b=-0.37, p<0.001).Conclusion: The results suggested that Western dietary pattern was related to higher BMI and Fat mass. Healthy pattern was associated with decreased levels of LBP. Adherence to Traditional dietary pattern was negatively related to DII.

کلیدواژه ها:

Dietary Inflammatory Index ، abdominal obesity ، adipokine ، Chemerin ، Omentin ، endotoxin ، dietary pattern